Number: 2001-066-1-700
Title: Global use of the C-NPU concept system for properties
in toxicology
Task Group
Chairman: Wolf R.
K�lpmann
Members: Rita
Cornelis, John H Duffus,
Ren� Dybkaer, Monica
Nordberg, Douglas
M. Templeton, and J.Christensen
Completion Date: 2007 - project completed
Objective:
To work out properties and units for global use of the C- NPU
concept system for properties in toxicology based on the former C-NPU
commission�s concepts and syntactic rules. The C-NPU commission, maintained
as a joint IFCC- IUPAC activity for two decades, has as its main task
to promote and maintain scientifically and conceptually sound ways
of expressing the outcome of measurements and other examinations in
laboratory medicine. The NPU coding scheme and vocabulary, based on
the SI system, concepts theory and high-level international standards,
is the main outcome and should be the cornerstone for expressing measurements
within international communication standards.
> See Series
on Properties and Units in the Clinical Laboratory Sciences
Description:
Representative substances of known importance in different areas
of toxicology will be selected and their properties and units compiled
in a data base according to the former C-NPU commission's concepts
and rules. The substances will be selected on the basis of their importance
for human health. The project conforms to the IUPAC strategic goals
2 and 4, i.e., to promote standardized nomenclature, symbols, terminology
and methodology in the chemical sciences as well as to facilitate
the development of effective channels of communication in the international
chemistry community.
Progress:
During the first meeting (Hannover, 2002-08-3/4) a first draft
by J.H. Duffus for properties in toxicology based on the general structure
elaborated by C-NPU was discussed. The C-NPU concept system was proven
to be appropriate for that purpose as demonstrated by a large number
of typical examples.
A draft titled "Properties and Units in the Clinical Laboratory
Sciences. Part XX. Properties and Units in Clinical and Environmental
Human Toxicology" has been completed and submitted to PAC
in Oct 2004; corresponding author: John
Duffus
Project completed - A technical report - number XX in the
series - is published in Pure
Appl. Chem.
79(1), 87-152, 2007.
Last Update: 9 January 2007
<project announcement published
in Chem.
Int.
24(6) 2002>