ORGANIC AND BIOMOLECULAR CHEMISTRY DIVISION
CHEMISTRY AND HUMAN HEALTH DIVISION
Postgenomic chemistry (IUPAC Technical Report)
Sergey Varfolomeyev1,*, Elena Efremenko1, Irina Beletskaya1, Ivano Bertini2, G. Michael Blackburn3, Alexey Bogdanov4, Raimond Cunin5, Jutta Eichler6, Igor Galaev7, Vadim Gladyshev8, David O'Hagan9, Thomas Haertle10, Jaak Jarv11, Arkadiy Karyakin1, Ilia Kurochkin1, Marian Mikolajczyk12, Vladimir Poroikov13, Ivan Sakharov1, Friedrich Spener14, Normand Voyer15, and James Wild16
1Chemical Enzymology Department, The M. V. Lomonosov Moscow State University, Lenin's Hills, 1/11, Moscow 119992, Russia; 2Magnetic Resonance Center, University of Florence, Italy; 3University of Sheffield, UK; 4Belozersky Institute, Moscow State University, Russia; 5Vrije University, Belgium; 6German Research Center of Biotechnology, Germany; 7Lund Universitiet Brussel, Sweden; 8University of Nebraska, USA; 9University of St. Andrews, UK; 10Institute of National Research Agronomy, France; 11University of Tartu, Estonia; 12Center of Molecular and Macromolecular Studies, Polish Academy of Sciences, Poland; 13Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Russia; 14University of Münster, Germany; 15Laval University, Canada; 16Texas A&M University, USA
Abstract: Numerous areas of chemistry can benefit from the ongoing genomic revolution. Here, we discuss and highlight trends in chemistry in the postgenomic era. The areas of interest include combinatorial approaches in organic chemistry; design and analysis of proteins containing unnatural amino acids; trace element-containing proteins; design and characterization of new enzyme types; applications of postgenomic chemistry in drug design; identification of lipid networks and global characterization of lipid molecular species; development of recombinant and self-proliferating polymers; and applications in food chemistry and bioanalytical chemistry based on new nanoanalytical systems and novel recognition elements.
Keywords: Postgenomic; combinatorial; bioanalytical; Division III; Division VII.
* Corresponding author.
Download full text of the report [pdf file - 181 kB]